amanf

2021-01-22

Consider the following research questions/study scenarios. For each study, discuss the most appropriate methods for describing the data (graphically and numerically). What statistical method would be most appropriate for addressing the research questions? Be sure to provide justification of the statistical method. Provide the appropriate regression model and statistical test when appropriate.
1.A study was performed to determine the differences in pain experienced by children with sickle cell disease (SCD) in inpatient and outpatient settings. Pain intensity (visual analog scale) was the primary outcome of interest, but potential confounders include age and physical activity.

### Answer & Explanation

Step 1
Given,
The difference between the pain felt by kids with sickle cell disease (SCD) in inpatient and outpatient settings was investigated. The primary outcome of interest was pain intensity (visual analog scale), although potential confounders included age and physical activity.
Step 2
It will be more reasonable to do a two sample t-test.
The patient category (inpatient or outpatient) acts as an independent variable in this situation, making the two samples independent.
We assume that the population is Normal with the same variance because the VAS is a quantitative (continuous data) measurement of pain intensity.
Age and physical activity are two potential confounders, therefore we must account for these as well as maybe define inclusion and exclusion criteria that restrict the groups in order to provide data that is free of confounders.
Bar charts are suitable for visually describing the data.

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