# The most appropriate study design depends, among other things, on the distribution of 1.

The most appropriate study design depends, among other things, on the distribution of
1.A) The risk factor in the population of interest
2.B) The participants
3.C) The outcome in the population of interest
4.D)

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Step 1 Introduction
Epidemiology is the branch of bio statistics that focuses on the $\frac{\text{study of health}}{\text{illness of human population}}$, disease and other factors. If we found that a particular thing which is related to the development of the disease, there are lots of way to collect information to evaluate the contact between risk factor and disease.
Step 2 Required option.
The most appropriate study design depends, among other things, on the distribution of both the risk factor and the outcome in the population of interest.
Hence the required option 4. D) both