1. A drug is being tested in a chronic disease whose condition waxes and wanes over time. Which of the following study designs is most effective in ev

Zoe Oneal 2021-03-07 Answered
1. A drug is being tested in a chronic disease whose condition waxes and wanes over time. Which of the following study designs is most effective in evaluating the efficacy and safety of a new therapy
for this disease?
A. Retrospective Cohort
B. Case-Control
C. Prospective, Randomized, Active Control, Parallel Group Design
D. Prospective, Randomized, Active Control, Crossover Design
You can still ask an expert for help

Expert Community at Your Service

  • Live experts 24/7
  • Questions are typically answered in as fast as 30 minutes
  • Personalized clear answers
Learn more

Solve your problem for the price of one coffee

  • Available 24/7
  • Math expert for every subject
  • Pay only if we can solve it
Ask Question

Expert Answer

Laaibah Pitt
Answered 2021-03-08 Author has 98 answers
Step 1
There are many different type of studies and different ways of their conduction.
For each of these type of studies,there are crucial features to look for in study design.
Step 2
For studies testing if new interventions are effective it not,most reliable design would be a randomized comparative trial.
In this trial,patients on which studies are going on,are allocated by chance to either the new interventions that is being tested,or the alternative comparative treatment.
Sometimes, comparative treatment is a kind of placebo drug or procedure or sometimes the best treatment available.
Step 3
For testing efficacy of drug treatment, surgical procedure: preferred design is randomized controlled trial
For diagnosis: Combination of randomized comparison of new test with old follow up of cohort
For screening : longitudinal cohort study of patient with Disease
For prognosis: longitudinal cohort study of patient
Causation:case control or cohort study
Step 4
So keeping all the points in mind
Correct option will be
D. Prospective, Randomized, Active Control, Crossover Design
Not exactly what you’re looking for?
Ask My Question

Expert Community at Your Service

  • Live experts 24/7
  • Questions are typically answered in as fast as 30 minutes
  • Personalized clear answers
Learn more

Relevant Questions

asked 2021-03-08

Prove that the reduced row echelon forms of the matrices(1 1 4 8 0 1 11 2 3 9 0 5 20 2 2 2 1 14 31 4 1 11 0 13 4) (0 3 3 1 50 1 1 0 00 2 2 0 3)

are the two matrices. 

The point of the reduced row echelon form is that the corresponding system of linear equations is in a particularly simple form, from which the solutions to the system AX=C in (4) can be determined immediately.

 

asked 2021-03-02
Determine whether the study depicts an observational study or an experimental study.
A study was done to see if sugar consumption can cause hypoeractivity in children. The researcher took four groups of children and assigned different amounts of sugar the children had to consume. After a certain period of​ time, they assessed whether or not the children were hyperactive.
asked 2021-07-02
Do piano lessons improve the spatial-temporal reasoning of preschool children? A study designed to investigate this question measured the spatial-temporal reasoning of a random sample of 34 preschool children before and after 6 months of piano lessons. The differences (After - Before) in the reasoning scores have mean 3.618 and standard deviation 3.055.
asked 2021-06-20
Define the following terms: a. Observational study, b. Designed experiment.
asked 2021-06-03

The American Journal of Political Science (Apr. 2014) published a study on a woman's impact in mixed-gender deliberating groups. The researchers randomly assigned subjects to one of several 5-member decision-making groups. The groups' gender composition varied as follows: 0 females, 1 female, 2 females, 3 females, 4 females, or 5 females. Each group was the n randomly assigned to utilize one of two types of decision rules: unanimous or majority rule. Ten groups were created for each of the 6 × 2=12 combinations of gender composition and decision rule. One variable of interest, measured for each group, was the number of words spoken by women on a certain topic per 1,000 total words spoken during the deliberations. a. Why is this experiment considered a designed study? b. Identify the experimental unit and dependent variable in this study. c. Identify the factors and treatments for this study.

asked 2021-06-16
Refer to the Journal of Experimental Social Psychology (Vol. 45, 2009) study of whether buying gifts truly buys love. Recall that study participants were randomly assigned to play the role of gift giver or gift receiver. Gift receivers were asked to provide the level of appreciation (measured on a 7-point scale where 1 = "not at all" and 7 = "to a great extent") they had for the last birthday gift they received from a loved one. Gift givers were asked to recall the last birthday gift they gave to a loved one and to provide the level of appreciation the loved one had for the gift. The researchers wanted to know if the average level of appreciation is higher for birthday gift givers than for birthday gift receivers. a. Why is this study designed? b. Specify the key elements of the study: experimental unit, response variable, factor, and treatments.
asked 2021-05-21
A proposed study design is to leave 100 questionnaires by the checkout line in a student cafeteria. The questionnaire can be picked up by any student and returned to the cashier. Explain why this volunteer sample is a poor study design.